{"id":333,"date":"2025-02-03T15:33:47","date_gmt":"2025-02-03T14:33:47","guid":{"rendered":"https:\/\/rir.lu\/?post_type=pathologie&p=333"},"modified":"2025-04-17T11:07:36","modified_gmt":"2025-04-17T09:07:36","slug":"ankylosing-spondylitis","status":"publish","type":"pathologie","link":"https:\/\/rir.lu\/en\/diseases\/ankylosing-spondylitis\/","title":{"rendered":"Ankylosing spondylitis"},"content":{"rendered":"\n
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Definition<\/p>\n<\/div>\n\n\n\n

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Ankylosing spondylitis is a chronic inflammatory disease that mainly affects the spinal column and sacroiliac joints. It causes pain and progressive stiffness, with the risk of fusion of the vertebrae over the long term.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Symptoms<\/p>\n\n\n\n

How does the disease manifest?<\/h2>\n<\/div>\n\n\n\n
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  • Chronic back pain<\/strong> (especially at night and when at rest)<\/li>\n\n\n\n
  • Morning stiffness<\/strong> (that improves with physical activity)<\/li>\n\n\n\n
  • Pain in the buttocks and hips<\/strong><\/li>\n\n\n\n
  • Fatigue<\/strong><\/li>\n\n\n\n
  • In advanced cases, loss of mobility and stooped posture<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
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    Factors<\/p>\n\n\n\n

    Risk factors<\/strong><\/h2>\n<\/div>\n\n\n\n
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    • Family history<\/strong>
      (presence of the HLA-B27 gene)<\/li>\n\n\n\n
    • Being male<\/strong>
      (men are more frequently affected)<\/li>\n\n\n\n
    • Age<\/strong>
      (symptoms start before the age of 45)<\/li>\n\n\n\n
    • Triggering intestinal or genital infections<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
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      Treatments<\/p>\n\n\n\n

      What treatments for the disease?<\/h2>\n<\/div>\n\n\n\n
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      • Non-steroidal anti-inflammatory drugs<\/strong> (NSAIDS)<\/li>\n\n\n\n
      • Physiotherapy and exercise<\/strong>
        (to maintain mobility)<\/li>\n\n\n\n
      • Biotherapies targeting<\/strong>
        (inflammatory cytokines)<\/li>\n\n\n\n
      • Analgesics<\/strong>
        (and in severe cases, surgery)<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

        Chronic inflammatory rheumatisms that affect the entheses<\/p>\n","protected":false},"featured_media":0,"template":"","categorie-pathologie":[34],"class_list":["post-333","pathologie","type-pathologie","status-publish","hentry","categorie-pathologie-imids-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie\/333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie"}],"about":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/types\/pathologie"}],"wp:attachment":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/media?parent=333"}],"wp:term":[{"taxonomy":"categorie-pathologie","embeddable":true,"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/categorie-pathologie?post=333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}