{"id":330,"date":"2025-02-03T15:48:13","date_gmt":"2025-02-03T14:48:13","guid":{"rendered":"https:\/\/rir.lu\/?post_type=pathologie&p=330"},"modified":"2025-04-17T11:03:53","modified_gmt":"2025-04-17T09:03:53","slug":"disseminated-lupus-erythematosus-dle","status":"publish","type":"pathologie","link":"https:\/\/rir.lu\/en\/diseases\/disseminated-lupus-erythematosus-dle\/","title":{"rendered":"Disseminated Lupus Erythematosus (DLE)"},"content":{"rendered":"\n
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Definition<\/p>\n<\/div>\n\n\n\n

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Disseminated Lupus Erythematosus (DLE) is a chronic autoimmune disease that can affect many organs of the body. It causes chronic inflammation due to an abnormal reaction of the immune system against the body’s own tissues.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Symptoms <\/p>\n\n\n\n

How does the disease manifest?<\/h2>\n<\/div>\n\n\n\n
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Main symptoms<\/strong>:<\/p>\n\n\n\n

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  • Chronic fatigue<\/strong><\/li>\n\n\n\n
  • High temperature<\/strong><\/li>\n\n\n\n
  • Joint pain<\/strong><\/li>\n\n\n\n
  • Skin disorders<\/strong>
    (in particular a \u201cbutterfly wing\u201d erythema on the face)<\/li>\n\n\n\n
  • Sensitivity to light<\/strong><\/li>\n<\/ul>\n<\/div>\n\n\n\n
    \n

    Other possible symptoms<\/strong>:<\/strong><\/p>\n\n\n\n

      \n
    • Kidney issues<\/strong><\/li>\n\n\n\n
    • Lung issues<\/strong><\/li>\n\n\n\n
    • Heart issues<\/strong><\/li>\n\n\n\n
    • Neurological issues<\/strong><\/li>\n\n\n\n
    • Haematological<\/strong> issues<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
      \n
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      Factors<\/p>\n\n\n\n

      Les facteurs de risques<\/h2>\n<\/div>\n\n\n\n
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      • Genetic predisposition<\/strong><\/li>\n\n\n\n
      • Being female<\/strong>
        (women are affected in 90% of cases)<\/li>\n\n\n\n
      • Exposure to sunlight<\/strong><\/li>\n\n\n\n
      • Certain medications or infections<\/strong><\/li>\n\n\n\n
      • Hormones<\/strong>
        (possible link to oestrogens)<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
        \n
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        Treatments <\/p>\n\n\n\n

        What treatments for the disease?<\/h2>\n<\/div>\n\n\n\n
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        Treatment objectives<\/strong>:<\/h3>\n\n\n\n

        Reduce inflammation, control flare-ups, prevent organ damage, improve quality of life.<\/p>\n<\/div>\n\n\n\n

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        Medication treatments<\/strong>:<\/h3>\n\n\n\n
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        • Non-steroidal anti-inflammatory drugs<\/strong>
          (NSAIDS)<\/li>\n\n\n\n
        • Corticosteroids<\/strong><\/li>\n\n\n\n
        • Immunosuppressants<\/strong><\/li>\n\n\n\n
        • Antimalaria drugs<\/strong>
          (hydroxychloroquine)<\/li>\n<\/ul>\n\n\n\n

          Non-medication treatments<\/strong>:<\/h3>\n\n\n\n
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          • Avoidance of triggering factors<\/strong>
            (sunlight, stress)<\/li>\n\n\n\n
          • Therapeutic education<\/strong>
            of the patient<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

            <\/p>\n","protected":false},"excerpt":{"rendered":"

            Rare disease that appears in different forms and can affect the skin and joints, but also internal organs<\/p>\n","protected":false},"featured_media":0,"template":"","categorie-pathologie":[32],"class_list":["post-330","pathologie","type-pathologie","status-publish","hentry","categorie-pathologie-osteoarticular-disorders"],"acf":[],"_links":{"self":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie\/330","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie"}],"about":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/types\/pathologie"}],"wp:attachment":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/media?parent=330"}],"wp:term":[{"taxonomy":"categorie-pathologie","embeddable":true,"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/categorie-pathologie?post=330"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}