{"id":326,"date":"2025-02-03T15:56:11","date_gmt":"2025-02-03T14:56:11","guid":{"rendered":"https:\/\/rir.lu\/?post_type=pathologie&p=326"},"modified":"2025-04-17T11:01:20","modified_gmt":"2025-04-17T09:01:20","slug":"gougerot-sjogrens-syndrome","status":"publish","type":"pathologie","link":"https:\/\/rir.lu\/en\/diseases\/gougerot-sjogrens-syndrome\/","title":{"rendered":"Gougerot-Sj\u00f6gren\u2019s Syndrome"},"content":{"rendered":"\n
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Definition<\/p>\n<\/div>\n\n\n\n

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Gougerot-Sj\u00f6gren\u2019s syndrome is a chronic autoimmune disease mainly characterised by dryness of the mucous membranes, especially of the eyes (xerophthalmia) and of the mouth (xerostomia). However, it can also affect other organs.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Symptoms<\/p>\n\n\n\n

How does the disease manifest?<\/h2>\n<\/div>\n\n\n\n
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Main symptoms<\/strong>:<\/h3>\n\n\n\n
    \n
  • Dry eyes<\/strong>
    (redness, grain of sand sensation)<\/li>\n\n\n\n
  • Dry mouth<\/strong>
    (difficulty swallowing, frequent tooth cavities)<\/li>\n\n\n\n
  • Chronic fatigue<\/strong><\/li>\n<\/ul>\n<\/div>\n\n\n\n
    \n

    Other possible symptoms<\/strong>:<\/strong><\/h3>\n\n\n\n
      \n
    • Joint problems<\/strong> (pain and stiffness)<\/li>\n\n\n\n
    • Problems with the salivary glands<\/strong> (swelling)<\/li>\n\n\n\n
    • Lung problems<\/strong><\/li>\n\n\n\n
    • Kidney problems<\/strong><\/li>\n\n\n\n
    • Neurological problems<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
      \n
      \n

      Factors<\/p>\n\n\n\n

      Risk factors<\/strong><\/h2>\n<\/div>\n\n\n\n
      \n
      \n
        \n
      • Genetic factors<\/strong><\/li>\n\n\n\n
      • Hormonal factors<\/strong> (more frequent in women)<\/li>\n\n\n\n
      • Environmental factors<\/strong><\/li>\n<\/ul>\n<\/div>\n\n\n\n
        \n
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        Disease mechanisms<\/strong>:<\/h3>\n\n\n\n

        The immune system mistakenly attacks the exocrine glands (tear ducts and salivary glands), reducing their secretions.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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        Treatments <\/p>\n\n\n\n

        What treatments for the disease?<\/h2>\n<\/div>\n\n\n\n
        \n

        Treatment objectives<\/strong>:<\/h3>\n\n\n\n

        Relieve symptoms, preserve the function of the affected organs, improve quality of life.<\/p>\n<\/div>\n\n\n\n

        \n
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        Medication treatments<\/strong>:<\/h3>\n\n\n\n
          \n
        • Artificial tears and saliva<\/strong><\/li>\n\n\n\n
        • Medications<\/strong>
          to stimulate gland secretions<\/strong><\/li>\n\n\n\n
        • Immunosuppressants<\/strong>
          (for the most severe cases)<\/li>\n<\/ul>\n\n\n\n

          Non-medication treatments<\/strong>:<\/h3>\n\n\n\n
            \n
          • Rigorous oral hygiene<\/strong><\/li>\n\n\n\n
          • Humidification of indoor air<\/strong><\/li>\n\n\n\n
          • Physiotherapy<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

            <\/p>\n","protected":false},"excerpt":{"rendered":"

            Autoimmune disease that often manifests through the triad of pain, dryness, and fatigue<\/p>\n","protected":false},"featured_media":0,"template":"","categorie-pathologie":[32],"class_list":["post-326","pathologie","type-pathologie","status-publish","hentry","categorie-pathologie-osteoarticular-disorders"],"acf":[],"_links":{"self":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie\/326","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie"}],"about":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/types\/pathologie"}],"wp:attachment":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/media?parent=326"}],"wp:term":[{"taxonomy":"categorie-pathologie","embeddable":true,"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/categorie-pathologie?post=326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}