{"id":325,"date":"2025-02-03T16:02:37","date_gmt":"2025-02-03T15:02:37","guid":{"rendered":"https:\/\/rir.lu\/?post_type=pathologie&p=325"},"modified":"2025-04-17T11:11:23","modified_gmt":"2025-04-17T09:11:23","slug":"dermato-polymyositis","status":"publish","type":"pathologie","link":"https:\/\/rir.lu\/en\/diseases\/dermato-polymyositis\/","title":{"rendered":"Dermato-polymyositis"},"content":{"rendered":"\n
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Definition<\/p>\n<\/div>\n\n\n\n

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Dermato-polymyositis is a rare and chronic autoimmune disease characterised by inflammation of the muscles (myositis) and of the skin (dermatitis). It belongs to a group of autoimmune diseases, in which the immune system mistakenly attacks healthy tissues.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Symptoms<\/p>\n\n\n\n

How does the disease manifest?<\/h2>\n<\/div>\n\n\n\n
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Main symptoms:<\/strong><\/h3>\n\n\n\n
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  • Progressive muscular weakness<\/strong>
    (especially in the upper and lower limbs)<\/li>\n\n\n\n
  • Muscle pain<\/strong><\/li>\n\n\n\n
  • Skin problems<\/strong> (erythema, oedema, calcifications)<\/li>\n\n\n\n
  • Chronic fatigue<\/strong><\/li>\n<\/ul>\n<\/div>\n\n\n\n
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    Other possible symptoms:<\/strong><\/strong><\/h3>\n\n\n\n
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    • High temperature<\/strong><\/li>\n\n\n\n
    • Weight loss<\/strong><\/li>\n\n\n\n
    • Attack on other organs<\/strong> (lungs, heart, oesophagus)<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
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      Factors<\/p>\n\n\n\n

      Risk factors<\/strong><\/h2>\n<\/div>\n\n\n\n
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      The exact cause is unknown, but genetic and environmental factors seem to play a role. Associations with certain cancers have been reported.<\/p>\n<\/div>\n\n\n\n

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      Disease mechanisms:<\/strong><\/h3>\n\n\n\n

      The immune system produces antibodies that attack muscle fibres and blood vessels in the skin, causing inflammation.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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      Treatments<\/p>\n\n\n\n

      What treatments for the disease?<\/h2>\n<\/div>\n\n\n\n
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      Treatment objectives:<\/strong><\/h3>\n\n\n\n

      Reduce inflammation, improve muscle strength, control skin problems and treat complications.<\/p>\n<\/div>\n\n\n\n

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      Medication treatments:<\/strong><\/h3>\n\n\n\n
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      • Corticosteroids<\/strong><\/li>\n\n\n\n
      • Immunosuppressants<\/strong><\/li>\n\n\n\n
      • Intravenous immunoglobulins<\/strong><\/li>\n\n\n\n
      • Biotherapies<\/strong><\/li>\n<\/ul>\n\n\n\n

        Non-medication treatments:<\/strong><\/h3>\n\n\n\n
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        • Physical therapy<\/strong><\/li>\n\n\n\n
        • Occupational therapy<\/strong><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

          Chronic disease that is part of what is known as autoimmune diseases<\/p>\n","protected":false},"featured_media":0,"template":"","categorie-pathologie":[32],"class_list":["post-325","pathologie","type-pathologie","status-publish","hentry","categorie-pathologie-osteoarticular-disorders"],"acf":[],"_links":{"self":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie\/325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/pathologie"}],"about":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/types\/pathologie"}],"wp:attachment":[{"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/media?parent=325"}],"wp:term":[{"taxonomy":"categorie-pathologie","embeddable":true,"href":"https:\/\/rir.lu\/en\/wp-json\/wp\/v2\/categorie-pathologie?post=325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}