Definition
Disseminated Lupus Erythematosus (DLE) is a chronic autoimmune disease that can affect many organs of the body. It causes chronic inflammation due to an abnormal reaction of the immune system against the body’s own tissues.
Symptoms
How does the disease manifest?
Main symptoms:
- Chronic fatigue
- High temperature
- Joint pain
- Skin disorders
(in particular a “butterfly wing” erythema on the face) - Sensitivity to light
Other possible symptoms:
- Kidney issues
- Lung issues
- Heart issues
- Neurological issues
- Haematological issues
Factors
Les facteurs de risques
- Genetic predisposition
- Being female
(women are affected in 90% of cases) - Exposure to sunlight
- Certain medications or infections
- Hormones
(possible link to oestrogens)
Treatments
What treatments for the disease?
Treatment objectives:
Reduce inflammation, control flare-ups, prevent organ damage, improve quality of life.
Medication treatments:
- Non-steroidal anti-inflammatory drugs
(NSAIDS) - Corticosteroids
- Immunosuppressants
- Antimalaria drugs
(hydroxychloroquine)
Non-medication treatments:
- Avoidance of triggering factors
(sunlight, stress) - Therapeutic education
of the patient